• TRADE NAMES: Ciclosporin; Consupren; Implanta; Neoral (Novartis); Restasis (Allergan); Sandimmun; Sandimmune (Novartis)
• INDICATIONS: Rheumatoid arthritis, prophylaxis of organ rejection in transplants, psoriasis; Restasis is indicated for patients with moderate-to-severe dry eye syndrome
  
• SYNONYM: Cyclosporine-A; CsA; CyA
• CLASS: Antipsoriatic agent, Calcineurin inhibitor, Disease-modifying antirheumatic drug (DMARD), Immunosuppressant
• HALF-LIFE: 10–27 hours (adults)

Afatinib, Aliskiren, Ambrisentan, Amiloride, Aminoglycosides, Amiodarone, Amphotericin B, Ampicillin, Amprenavir, Anisindione, Anticoagulants, Armodafinil, Atazanavir, Atorvastatin, Azathioprine, Azithromycin, Bacampicillin, Basiliximab, Benazepril, Berotralstat, Bezafibrate, Boceprevir, Bosentan, Bupropion, Captopril, Carbenicillin, Caspofungin, Ceritinib, Cholestyramine, Cholic Acid, Choline Fenofibrate, Cilazapril, Ciprofloxacin, Clarithromycin, Cloxacillin, Co-Trimoxazole, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colchicine, Colesevelam, Corticosteroids, Crizotinib, Cyclophosphamide, Dabigatran, Daclizumab, Danazol, Daptomycin, Darifenacin, Darunavir, Dasatinib, Delavirdine, Dichlorphenamide, Diclofenac, Dicloxacillin, Dicumarol, Digoxin, Diltiazem, Disulfiram, Docetaxel, Doxycycline, Dronedarone, Echinacea, Efavirenz, Elbasvir & Grazoprevir, Eluxadoline, Enalapril, Enzalutamide, Erythromycin, Ethotoin, Etoposide, Etoricoxib, Everolimus, Ezetimibe, Flunisolide, Fluoxymesterone, Fluvastatin, Foscarnet, Fosinopril, Fosphenytoin, Gemfibrozil, Glecaprevir & Pibrentasvir, Grapefruit Juice, Hemophilus B Vaccine, HMG-CoA reductase inhibitors, Imatinib, Imipenem/Cilastatin, Indinavir, Influenza Vaccine, Irbesartan, Itraconazole, Ketoconazole, Lanreotide, Letermovir, Levofloxacin, Lisinopril, Lopinavir, Lovastatin, Lumateperone, Meloxicam, Mephenytoin, Methicillin, Methoxsalen, Methylphenidate, Methylprednisolone, Methyltestosterone, Mezlocillin, Micafungin, Mifepristone, Mizolastine, Moxifloxacin, Mycophenolate, Nafcillin, Naldemedine, Natalizumab, Nelfinavir, Neratinib, Nevirapine, Nifedipine, Nisoldipine, Norfloxacin, NSAIDs, Ofloxacin, Olmesartan, Omeprazole, Orlistat, Osimertinib, Oxacillin, Oxcarbazepine, Ozanimod, Pasireotide, Penicillins, Phenytoin, Pitavastatin, Posaconazole, Pravastatin, Prednisolone, Prednisone, Pristinamycin, Quinapril, Rabeprazole, Ramipril, Ranolazine, Revefenacin, Ribociclib, Rifabutin, Rifampin, Rifapentine, Ritonavir, Rosuvastatin, Sevelamer, Silodosin, Simvastatin, Sirolimus, Sofosbuvir/Velpatasvir/Voxilaprevir, Spironolactone, St John's Wort, Sulfacetamide, Sulfadiazine, Sulfamethoxazole, Sulfisoxazole, Sulfonamides, Tacrolimus, Telithromycin, Temsirolimus, Tenoxicam, Terbinafine, Testosterone, Ticarcillin, Tinidazole, Tipranavir, Tofacitinib, Tolvaptan, Trabectedin, Trandolapril, Triamterene, Trimethoprim, Troleandomycin, Ubrogepant, Ursodiol, Vaccines, Vecuronium, Venetoclax, Voriconazole, Warfarin, Zofenopril

PREGNANCY CATEGORY: C