CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH: Alcohol, Aldesleukin , Allopurinol , Alpha blockers, Alprostadil , Amifostine , Amiloride , Angiotensin II receptor antagonists, Antacids, Antihypertensives, Antipsychotics, Azathioprine , Baclofen , Beta blockers, Calcium channel blockers, Clonidine , Corticosteroids, Cyclosporine , Diazoxide , Diuretics, Eplerenone , Estrogens , Everolimus , General anesthetics, Gold & Gold Compounds , Heparins, Hydralazine , Hypotensives, Insulin , Levodopa , Lithium , MAO inhibitors, Metformin , Methyldopa , Minoxidil , Moxisylyte , Moxonidine , Nitrates, Nitroprusside , NSAIDs, Pentoxifylline , Phosphodiasterase 5 inhibitors, Potassium salts, Prostacyclin analogues, Quinine , Rituximab , Sirolimus , Spironolactone , Sulfonylureas, Telmisartan , Temsirolimus , Tizanidine , Tolvaptan , Triamterene , Trimethoprim PREGNANCY: category C in first trimester; category D in second and third trimesters
Notes
Contra-indicated in patients with a history of angioedema related to previous treatment with an ACE inhibitor, or a history of hereditary or idiopathic angioedema.
Black Box Warning
See full prescribing information for complete boxed warning.
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Page last updated 02/06/2025