Eplerenone
- TRADE NAME: Inspra (Pfizer)
- INDICATIONS: Hypertension
- CLASS: Aldosterone antagonist / mineralocorticoid receptor antagonist (MRA), Diuretic
- HALF-LIFE: 4–6 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
ACE Inhibitors, Angiotensin II receptor antagonist, Aprepitant, Benazepril, Captopril, Conivaptan, Darunavir, Delavirdine, Efavirenz, Enalapril, Erythromycin, Fluconazole, Grapefruit Juice, Indinavir, Irbesartan, Itraconazole, Ketoconazole, Lapatinib, Lisinopril, Meloxicam, Nelfinavir, Olmesartan, Quinapril, Ramipril, Saquinavir, St John's Wort, Telithromycin, Tipranavir, Trimethoprim, Verapamil, Voriconazole
PREGNANCY CATEGORY: B
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CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric