Efavirenz

BreastfeedingGeriatricPediatric
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Alprazolam, Amprenavir, Aripiprazole, Artesunate, Atazanavir, Atorvastatin, Atovaquone, Avapritinib, Benzodiazepines, Bepridil, Boceprevir, Bortezomib, Brentuximab Vedotin, Budesonide, Buprenorphine, Bupropion, Carbamazepine, Carvedilol, Caspofungin, Chlordiazepoxide, Cisapride, Citalopram, Clarithromycin, Clonazepam, Clopidogrel, Clorazepate, CNS depressants, Cobimetinib, Colchicine, Conivaptan, Crizotinib, Cyclosporine, CYP2B6 inhibitors and inducers, CYP2C19 substrates, CYP2C9 substrates, CYP3A4 substrates and inducers, Darunavir, Dasatinib, Deferasirox, Deflazacort, Diazepam, Dihydroergotamine, Diltiazem, Doravirine, Dronedarone, Elbasvir & Grazoprevir, Enzalutamide, Eplerenone, Ergot, Etravirine, Everolimus, Exemestane, Fentanyl, Finerenone, Flurazepam, Fosamprenavir, Fosphenytoin, Gefitinib, Glecaprevir & Pibrentasvir, Grapefruit Juice, Guanfacine, Halofantrine, Hydroxyzine, Ibrexafungerp, Imatinib, Indinavir, Itraconazole, Ixabepilone, Lapatinib, Lemborexant, Levomepromazine, Levonorgestrel, Linagliptin, Lopinavir, Lorazepam, Lovastatin, Lumateperone, Lurasidone, Maraviroc, Methadone, Methysergide, Midazolam, Mifepristone, Neratinib, Nevirapine, Nifedipine, Nilotinib, Nisoldipine, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir, Oral Contraceptives, Oxazepam, Paclitaxel, Palbociclib, Pazopanib, Phenytoin, Pimecrolimus, Pimozide, Posaconazole, Pravastatin, Praziquantel, Progestogens, Propafenone, Protease inhibitors, Quazepam, Raltegravir, Ranolazine, Rifabutin, Rifampin, Rilpivirine, Ritonavir, Rivaroxaban, Roflumilast, Romidepsin, Salmeterol, Saquinavir, Saxagliptin, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sofosbuvir & Velpatasvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Sonidegib, Sorafenib, SSRIs, St John's Wort, Sunitinib, Tacrolimus, Tadalafil, Telaprevir, Temazepam, Ticagrelor, Tipranavir, Tocilizumab, Tolvaptan, Toremifene, Triazolam, Ulipristal, Vandetanib, Vemurafenib, Venetoclax, Vilazodone, Vitamin K antagonists, Voriconazole, Warfarin, Zuclopenthixol

PREGNANCY CATEGORY: D

Atripla is efavirenz, emtricitabine and tenofovir disoproxil.

Our database has 90 adverse reactions for this drug across the following areas

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SKIN.
HAIR.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
RESPIRATORY.
OTHER.


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Click on this DRUG REVIEW ARTICLE tab (above) to see a review of efavirenz in the Informa Healthcare journal Expert Opinion on Drug Safety (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 07/31/2023

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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