• TRADE NAMES: Atripla (Gilead); Sustiva (Bristol-Myers Squibb)
• INDICATIONS: HIV infection
  
• CLASS: Antiretroviral, CYP1A2 inhibitor, CYP3A4 inducer, Non-nucleoside reverse transcriptase inhibitor
• HALF-LIFE: 52–76 hours

Alcohol, Alprazolam, Amprenavir, Aripiprazole, Artesunate, Atazanavir, Atorvastatin, Atovaquone, Avapritinib, Benzodiazepines, Bepridil, Boceprevir, Bortezomib, Brentuximab Vedotin, Budesonide, Buprenorphine, Bupropion, Carbamazepine, Carvedilol, Caspofungin, Chlordiazepoxide, Cisapride, Citalopram, Clarithromycin, Clonazepam, Clopidogrel, Clorazepate, CNS depressants, Cobimetinib, Colchicine, Conivaptan, Crizotinib, Cyclosporine, CYP2B6 inhibitors and inducers, CYP2C19 substrates, CYP2C9 substrates, CYP3A4 substrates and inducers, Darunavir, Dasatinib, Deferasirox, Deflazacort, Diazepam, Dihydroergotamine, Diltiazem, Doravirine, Dronedarone, Elbasvir & Grazoprevir, Enzalutamide, Eplerenone, Ergot, Etravirine, Everolimus, Exemestane, Fentanyl, Finerenone, Flurazepam, Fosamprenavir, Fosphenytoin, Gefitinib, Glecaprevir & Pibrentasvir, Grapefruit Juice, Guanfacine, Halofantrine, Hydroxyzine, Ibrexafungerp, Imatinib, Indinavir, Itraconazole, Ixabepilone, Lapatinib, Lemborexant, Levomepromazine, Levonorgestrel, Linagliptin, Lopinavir, Lorazepam, Lovastatin, Lumateperone, Lurasidone, Maraviroc, Methadone, Methysergide, Midazolam, Mifepristone, Neratinib, Nevirapine, Nifedipine, Nilotinib, Nisoldipine, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir, Oral Contraceptives, Oxazepam, Paclitaxel, Palbociclib, Pazopanib, Phenytoin, Pimecrolimus, Pimozide, Posaconazole, Pravastatin, Praziquantel, Progestogens, Propafenone, Protease inhibitors, Quazepam, Raltegravir, Ranolazine, Rifabutin, Rifampin, Rilpivirine, Ritonavir, Rivaroxaban, Roflumilast, Romidepsin, Salmeterol, Saquinavir, Saxagliptin, Sertraline, Simeprevir, Simvastatin, Sirolimus, Sofosbuvir & Velpatasvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Sonidegib, Sorafenib, SSRIs, St John's Wort, Sunitinib, Tacrolimus, Tadalafil, Telaprevir, Temazepam, Ticagrelor, Tipranavir, Tocilizumab, Tolvaptan, Toremifene, Triazolam, Ulipristal, Vandetanib, Vemurafenib, Venetoclax, Vilazodone, Vitamin K antagonists, Voriconazole, Warfarin, Zuclopenthixol

PREGNANCY CATEGORY: D