Ibrexafungerp
- TRADE NAME: Brexafemme (Scynexis)
- INDICATIONS: Vulvovaginal candidiasis
- CLASS: Antifungal / antimycotic, Antimicrobial
- HALF-LIFE: approximately 20 hours
FDA APPROVAL DATE: 06/01/2021
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:Bosentan, Carbamazepine, CYP3A inducers, CYP3A inhibitors, Efavirenz, Etravirine, Itraconazole, Ketoconazole, long acting barbiturates , Phenytoin, Rifampin, St John's Wort
May cause fetal harm based on animal studies. Advise females of reproductive potential to use effective contraception during treatment.
Prior to initiating treatment, verify pregnancy status in females of reproductive potential.
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SKIN.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
NEUROMUSCULAR/SKELETAL.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric