• TRADE NAME: Vaprisol (Astellas)
• INDICATIONS: Hyponatremia, SIADH
  
• CLASS: CYP3A4 inhibitor, Vasopressin receptor antagonist
• HALF-LIFE: 5 hours

Acetaminophen, Albendazole, Alfuzosin, Almotriptan, Alosetron, Ambrisentan, Amitriptyline, Amlodipine, Antifungals, Aprepitant, Artemether/Lumefantrine, Atorvastatin, Bexarotene, Bortezomib, Brigatinib, Brinzolamide, Bupivacaine, Cabazitaxel, Cabozantinib, Ciclesonide, Cilostazol, Cinacalcet, Citalopram, Clarithromycin, Colchicine, Copanlisib, Cyclobenzaprine, CYP3A4 inhibitors or substrates, Darunavir, Dasatinib, Deferasirox, Delavirdine, Dienogest, Digoxin, Docetaxel, Dolasetron, Dronedarone, Dutasteride, Efavirenz, Enalapril, Eplerenone, Estradiol, Eszopiclone, Everolimus, Fentanyl, Fesoterodine, Fingolimod, Flibanserin, Gefitinib, Guanfacine, Halofantrine, Indinavir, Itraconazole, Ixabepilone, Ketoconazole, Lapatinib, Lomitapide, Maraviroc, Meloxicam, Metaxalone, Methylprednisolone, Micafungin, Midazolam, Midostaurin, Mifepristone, Mometasone, Neratinib, Nilotinib, Nisoldipine, Oxybutynin, Pantoprazole, Paricalcitol, Pazopanib, Pimecrolimus, Pioglitazone, Ponatinib, Prasugrel, Ramelteon, Ranolazine, Ribociclib, Ritonavir, Rivaroxaban, Romidepsin, Rosuvastatin, Ruxolitinib, Salmeterol, Saxagliptin, Sildenafil, Silodosin, Simvastatin, Sorafenib, St John's Wort, Tadalafil, Tamsulosin, Telithromycin, Temsirolimus, Terbinafine, Tiagabine, Tiotropium, Tipranavir, Tolvaptan, Trimethoprim, Ulipristal, Vardenafil, Venetoclax, Vorapaxar, Voriconazole, Ziprasidone

PREGNANCY CATEGORY: C