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- TRADE NAME: Vaprisol (Astellas)
- INDICATIONS: Hyponatremia, SIADH
- CLASS: CYP3A4 inhibitor, Vasopressin receptor antagonist
- HALF-LIFE: 5 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acetaminophen, Albendazole, Alfuzosin, Almotriptan, Alosetron, Ambrisentan, Amitriptyline, Amlodipine, Antifungals, Aprepitant, Artemether/Lumefantrine, Atorvastatin, Bexarotene, Bortezomib, Brigatinib, Brinzolamide, Bupivacaine, Cabazitaxel, Cabozantinib, Ciclesonide, Cilostazol, Cinacalcet, Citalopram, Clarithromycin, Colchicine, Copanlisib, Cyclobenzaprine, CYP3A4 inhibitors or substrates, Darunavir, Dasatinib, Deferasirox, Delavirdine, Dienogest, Digoxin, Docetaxel, Dolasetron, Dronedarone, Dutasteride, Efavirenz, Enalapril, Eplerenone, Estradiol, Eszopiclone, Everolimus, Fentanyl, Fesoterodine, Fingolimod, Flibanserin, Gefitinib, Guanfacine, Halofantrine, Indinavir, Itraconazole, Ixabepilone, Ketoconazole, Lapatinib, Lomitapide, Maraviroc, Meloxicam, Metaxalone, Methylprednisolone, Micafungin, Midazolam, Midostaurin, Mifepristone, Mometasone, Neratinib, Nilotinib, Nisoldipine, Oxybutynin, Pantoprazole, Paricalcitol, Pazopanib, Pimecrolimus, Pioglitazone, Ponatinib, Prasugrel, Ramelteon, Ranolazine, Ribociclib, Ritonavir, Rivaroxaban, Romidepsin, Rosuvastatin, Ruxolitinib, Salmeterol, Saxagliptin, Sildenafil, Silodosin, Simvastatin, Sorafenib, St John's Wort, Tadalafil, Tamsulosin, Telithromycin, Temsirolimus, Terbinafine, Tiagabine, Tiotropium, Tipranavir, Tolvaptan, Trimethoprim, Ulipristal, Vardenafil, Venetoclax, Vorapaxar, Voriconazole, Ziprasidone
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Page last updated 07/31/2023
