Lomitapide

BreastfeedingPediatric
  • TRADE NAME: Juxtapid (Aegerion)
  • INDICATIONS: Homozygous familial hypercholesterolemia
  • CLASS: Lipid regulator
  • HALF-LIFE: 39.7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Bile acid sequestrants, Boceprevir, Clarithromycin, Conivaptan, Grapefruit Juice, Indinavir, Itraconazole, Ketoconazole, Lopinavir, Lovastatin, Mibefradil, Nefazodone, Nelfinavir, Oral Contraceptives, P-glycoprotein substrates, Posaconazole, Ritonavir, Saquinavir, Simvastatin, Strong or moderate CYP3A4 inhibitors, Telaprevir, Telithromycin, Voriconazole, Warfarin

PREGNANCY CATEGORY: X

RISK OF HEPATOTOXICITY

See full prescribing information for complete boxed warning.

Our database has 28 adverse reactions for this drug across the following areas

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MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of lomitapide in the Taylor & Francis journal Expert Opinion on Drug Safety

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Page last updated 12/18/2019

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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