In order to deliver a personalised, responsive service and to improve the site, we remember and store information about how you use it. This is done using simple text files called cookies which sit on your computer. By continuing to use this site and access its features, you are consenting to our use of cookies. To find out more about the way drugeruptiondata.com uses cookies please read our 'Cookie Policy'.
Litt's app available free to subscribers - download for IOS and Android from the App Store or Google Play.
- TRADE NAMES: Aldocumar; Coumadin (Bristol-Myers Squibb); Coumadine; Marevan; Waran; Warfilone
- INDICATIONS: Thromboembolic disease, pulmonary embolism
- CLASS: Anticoagulant (antithrombotic), Coumarin
- HALF-LIFE: 1.5–2.5 days (highly variable)
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acemetacin, Amiodarone, Amobarbital, Amprenavir, Antithyroid agents, Aprepitant, Aprobarbital, Aspirin, Atazanavir, Atorvastatin, Azathioprine, Azithromycin, Barbiturates, Beclomethasone, Betamethasone, Bezafibrate, Bismuth, Bivalirudin, Boceprevir, Bosentan, Butabarbital, Capecitabine, Cefixime, Celecoxib, Ceritinib, Chondroitin, Cimetidine, Ciprofloxacin, Clarithromycin, Clofibrate, Clopidogrel, Clorazepate, Co-Trimoxazole, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colesevelam, Cyclosporine, Danazol, Daptomycin, Darunavir, Dasiglucagon, Delavirdine, Desvenlafaxine, Dexamethasone, Dexibuprofen, Dexlansoprazole, Diclofenac, Dicloxacillin, Dirithromycin, Disulfiram, Dronedarone, Duloxetine, Econazole, Efavirenz, Enzalutamide, Ergotamine, Erlotinib, Erythromycin, Eslicarbazepine, Etoricoxib, Exenatide, Fenofibrate, Fluconazole, Flunisolide, Fluoxymesterone, Fosamprenavir, Gefitinib, Gemfibrozil, Glucagon, Grapefruit Juice, Heparin, Imatinib, Influenza Vaccine, Inotersen, Itraconazole, Ketoconazole, Leflunomide, Lepirudin, Letermovir, Levofloxacin, Levothyroxine, Liothyronine, Liraglutide, Lomitapide, Lopinavir, Menadione, Mephobarbital, Methimazole, Methyl salicylate, Methylprednisolone, Methyltestosterone, Metronidazole, Miconazole, Mifepristone, Moricizine, Moxifloxacin, Nafcillin, Nalidixic Acid, Nandrolone, Nilutamide, Norfloxacin, Obeticholic Acid, Ofloxacin, Omeprazole, Oritavancin, Orlistat, Pantoprazole, PEG-Interferon, Penicillin G, Penicillin V, Penicillins, Pentobarbital, Phenobarbital, Phenylbutazones, Phytonadione, Piperacillin, Piroxicam, Prasugrel, Primidone, Propoxyphene, Propranolol, Propylthiouracil, Quinidine, Quinine, Rabeprazole, Resveratrol, Rifampin, Rifapentine, Rofecoxib, Romidepsin, Ropinirole, Rosuvastatin, Roxithromycin, Salicylates, Secobarbital, Simvastatin, Sitaxentan, Sorafenib, St John's Wort, Stanozolol, Sulfamethoxazole, Sulfinpyrazone, Sulfisoxazole, Sulfonamides, Sulindac, Tamsulosin, Tegafur/Gimeracil/Oteracil, Telaprevir, Telithromycin, Teriflunomide, Testosterone, Tibolone, Tigecycline, Tinidazole, Tolmetin, Tolterodine, Tramadol, Triamcinolone, Troleandomycin, Uracil/Tegafur, Valdecoxib, Vemurafenib, Venlafaxine, Vilazodone, Vitamin A, Vitamin E, Zafirlukast, Zileuton - PREGNANCY: category D for women with mechanical heart valves
- See adverse reactions attributed to class:
June 2024. Tramadol and warfarin drug interaction. The UK MHRA issued the following advice:
Taking warfarin and tramadol together can cause harmful drug interactions, which can raise the International Normalised Ratio (INR), and result in severe bruising and bleeding, which in some patients could be fatal.
Alternative remedies, including herbals, may potentially increase the risk of bleeding or potentiate the effects of warfarin therapy. Some of these include the following: angelica root, arnica flower, anise, asafetida, bogbean, borage seed oil, bromelain, dan-shen, devil’s claw, fenugreek, feverfew, garlic, ginger, ginkgo biloba, ginseng, horse chestnut, lovage root, meadowsweet, onion, parsley, passionflower herb, poplar, quassia, red clover, rue, turmeric and willow bark
BLEEDING RISK
See full prescribing information for complete boxed warning.
Please login to view the rest of this drug profile.
Page last updated 07/24/2024
