Sulfamethoxazole

CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Anticoagulants, Azathioprine, Cyclosporine, Methotrexate, Pralatrexate, Probenecid, Warfarin

PREGNANCY CATEGORY: C

Sulfamethoxazole is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

Sulfamethoxazole is commonly used in conjunction with trimethoprim (see separate entry for co-trimoxazole).

Our database has 72 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RENAL.
OTHER.


Page last updated 04/14/2020

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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