Patients receiving immunosuppressants, including azathioprine, are at increased risk of developing lymphoma and other malignancies, particularly of the skin.
- TRADE NAMES: Azamedac; Azamune; Azasan (aaiPharma); Azatrilem; Imuprin; Imuran (Prometheus); Imurek; Imurel; Thioprine
- INDICATIONS: Lupus nephritis, psoriatic arthritis, rheumatoid arthritis, autoimmune diseases, as an adjunct for the prevention of rejection in kidney transplant patients
- CLASS: Antimetabolite, Disease-modifying antirheumatic drug (DMARD), Immunosuppressant, Purine analog, Thiopurine
- HALF-LIFE: 12 minutes
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Allopurinol, Aminosalicylates, Balsalazide, Benazepril, Captopril, Chlorambucil, Co-Trimoxazole, Cyclophosphamide, Cyclosporine, Enalapril, Febuxostat, Fosinopril, Hemophilus B Vaccine, Imidapril, Lisinopril, Mesalamine, Mycophenolate, Natalizumab, Olsalazine, Quinapril, Ramipril, Ribavirin, Sulfamethoxazole, Tofacitinib, Trimethoprim, Typhoid Vaccine, Vaccines, Warfarin, Yellow Fever Vaccine
- See adverse reactions attributed to class:
MALIGNANCY
See full prescribing information for complete boxed warning.
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Page last updated 12/16/2025
