Lexxel is enalapril and felodipine; Teczem is enalapril and diltiazem; Vaseretic is enalapril and hydrochlorothiazide.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Contra-indicated in patients with a history of angioedema with or without previous ACE inhibitor treatment.
FETAL TOXICITY
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