Hydralazine
- TRADE NAMES: Alphapress; Apdormin; Apresazide (Novartis); Apresolin; Apresoline (Novartis); Novo-Hylazin; Nu-Hydral; Ser-Ap-Es (Novartis); Solesorin; Stable
- INDICATIONS: Hypertension
- CLASS: Vasodilator
- HALF-LIFE: 3–7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acebutolol, Alfuzosin, Captopril, Cilazapril, Diclofenac, Enalapril, Fosinopril, Levodopa, Levomepromazine, Lisinopril, Meloxicam, Olmesartan, Quinapril, Ramipril, Trandolapril, Triamcinolone, Trifluoperazine, Zuclopenthixol
PREGNANCY CATEGORY: C
Apresazide is hydralazine and hydrochlorothiazide; Ser-Ap-Es is hydralazine, reserpine and hydrochlorothiazide.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
Please login to see the rest of this drug profile
SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
