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- TRADE NAMES: Alphapress; Apdormin; Apresazide (Novartis); Apresolin; Apresoline (Novartis); Novo-Hylazin; Nu-Hydral; Ser-Ap-Es (Novartis); Solesorin; Stable
- INDICATIONS: Hypertension
- CLASS: Vasodilator
- HALF-LIFE: 3–7 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acebutolol, Alfuzosin, Captopril, Cilazapril, Diclofenac, Enalapril, Fosinopril, Levodopa, Levomepromazine, Lisinopril, Meloxicam, Olmesartan, Quinapril, Ramipril, Trandolapril, Triamcinolone, Trifluoperazine, Zuclopenthixol
Apresazide is hydralazine and hydrochlorothiazide; Ser-Ap-Es is hydralazine, reserpine and hydrochlorothiazide.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
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Page last updated 07/31/2023
