• TRADE NAMES: Alphapress; Apdormin; Apresazide (Novartis); Apresolin; Apresoline (Novartis); Novo-Hylazin; Nu-Hydral; Ser-Ap-Es (Novartis); Solesorin; Stable
  • INDICATIONS: Hypertension
  • CLASS: Vasodilator
  • HALF-LIFE: 3–7 hours

Apresazide is hydralazine and hydrochlorothiazide; Ser-Ap-Es is hydralazine, reserpine and hydrochlorothiazide.

Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

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Page last updated 07/31/2023

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Incidence

<1% 1‑5% 5‑10% 10‑15% 15‑20% 20‑30% >30%

Seriousness

Hospitalization possible
Life threatening
Fatal

Warnings in other populations

BreastfeedingBreast feeding

GeriatricGeriatric

PediatricPediatric