Trifluoperazine
- TRADE NAMES: Calmazine; Domilium; Flupazine; Fluzine; Nerolet; Psyrazine; Sedizine; Stelazine; TFP
- INDICATIONS: Psychoses, anxiety
- CLASS: Antipsychotic, Neuroleptic, Phenothiazine
- HALF-LIFE: 10–20 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
ACE inhibitors, Adrenergic neurone blockers, Antihistamines, Arsenic, Beta blockers, Chlorpheniramine, Diazoxide, Diuretics, Dofetilide, Hydralazine, Kaolin, Lithium, Minoxidil, Moxonidine, Myelosuppressives, Nitrates, Nitroprusside, Pentamidine, Pimozide, Piperazine, Quinolones, Sotalol, Sparfloxacin
PREGNANCY CATEGORY: C
INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
See full prescribing information for complete boxed warning.
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTHER.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
