Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.
Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.
- TRADE NAMES: Spara; Sparlox; Torospar; Zagam (LGM Pharma)
- INDICATIONS: Community-acquired pneumonia
- CLASS: Antibiotic, Antibiotic; fluoroquinolone, Antimicrobial
- HALF-LIFE: 16–30 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amiodarone, Amisulpride, Amitriptyline, Amoxapine, Arsenic, Bepridil, Bretylium, Calcium, Chlorpromazine, Clomipramine, Desipramine, Disopyramide, Doxepin, Erythromycin, Fluphenazine, Imipramine, Iron salts, Magnesium, Mesoridazine, Nortriptyline, Pentamidine, Perphenazine, Phenothiazines, Pimozide, Procainamide, Prochlorperazine, Promazine, Promethazine, Protriptyline, Quinidine, Sotalol, Sucralfate, Thioridazine, Tricyclic antidepressants, Trifluoperazine, Trimipramine, Zinc salts
- See adverse reactions attributed to class:
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Page last updated 08/07/2024
