Chlorpromazine

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Chloractil; Chlorazin; Chlorpromanyl; Esmino; Largactil; Novo-Chlorpromazine; Ormazine; Propaphenin; Prozin; Thorazine (GSK)
  • INDICATIONS: Psychosis, manic-depressive disorders
  • CLASS: Antiemetic, Antipsychotic, Muscarinic antagonist, Phenothiazine
  • HALF-LIFE: initial: 2 hours; terminal: 30 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Antihistamines, Arsenic, Asenapine, Chlorpheniramine, Dofetilide, Epinephrine, Evening Primrose, Guanethidine, Lisdexamfetamine, Mivacurium, Pimavanserin, Propranolol, Quinolones, Sodium Picosulfate, Sparfloxacin, Tetrabenazine, Zolpidem

PREGNANCY CATEGORY: N/A

The prolonged use of chlorpromazine can produce a gray-blue or purplish pigmentation over light-exposed areas. This is a result of either dermal deposits of melanin, a chlorpromazine metabolite, or to a combination of both. Chlorpromazine melanosis is seen more often in women.

INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS

See full prescribing information for complete boxed warning.

Our database has 89 adverse reactions for this drug across the following areas

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SKIN.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RESPIRATORY.
OTHER.


Page last updated 08/02/2021

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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