Pimavanserin



- TRADE NAME: Nuplazid (Acadia)
- INDICATIONS: Hallucinations and delusions associated with Parkinson’s disease psychosis
- CLASS: Antipsychotic
- HALF-LIFE: 57 hours
FDA APPROVAL DATE: 04/29/2016
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:Amiodarone, Carbamazepine, Chlorpromazine, Clarithromycin, Disopyramide, Drugs known to prolong the QT interval, Gatifloxacin, Indinavir, Itraconazole, Ketoconazole, Moxifloxacin, Phenytoin, Procainamide, Quinidine, Rifampin, Sotalol, St John's Wort, Strong CYP3A4 inhibitors and inducers, Thioridazine, Ziprasidone
PREGNANCY CATEGORY: N/A
No available data to inform drug-associated risk
INCREASED MORTALITY IN ELDERLY PATIENTS WITH DEMENTIA-RELATED PSYCHOSIS
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SKIN.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
OTHER.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric