Amiodarone

BreastfeedingGeriatricPediatric
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Abarelix, Acebutolol, Acenocoumarol, Afatinib, Amisulpride, Amitriptyline, Amprenavir, Anisindione, Anticoagulants, Arsenic, Artemether/Lumefantrine, Asenapine, Astemizole, Atazanavir, Atorvastatin, Azoles, Betrixaban, Boceprevir, Bosentan, Carbimazole, Celiprolol, Cholestyramine, Cimetidine, Ciprofloxacin, Clopidogrel, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colchicine, Cyclosporine, Dabigatran, Daclatasvir, Darunavir, Degarelix, Delavirdine, Dextromethorphan, Dicumarol, Digoxin, Diltiazem, Disopyramide, Dronedarone, Droperidol, Echinacea, Enoxacin, Fentanyl, Flecainide, Fosamprenavir, Gatifloxacin, Grapefruit Juice, Indinavir, Ledipasvir & Sofosbuvir, Lesinurad, Letermovir, Levofloxacin, Levomepromazine, Lidocaine, Lomefloxacin, Lopinavir, Loratadine, Macrolide antibiotics, Methotrexate, Moxifloxacin, Naldemedine, Nelfinavir, Nevirapine, Nilotinib, Norfloxacin, Ofloxacin, Orlistat, Oxprenolol, Pentamidine, Phenytoin, Pimavanserin, Procainamide, Propranolol, Quinidine, Quinine, Quinolones, Ribociclib, Rifabutin, Rifampin, Rifapentine, Ritonavir, Ropivacaine, Rosuvastatin, Simvastatin, Sofosbuvir & Velpatasvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Sotalol, Sparfloxacin, St John's Wort, Sulpiride, Tacrolimus, Telaprevir, Tetrabenazine, Thalidomide, Tipranavir, Trazodone, Vandetanib, Venetoclax, Verapamil, Warfarin, Zuclopenthixol

PREGNANCY CATEGORY: D

Amiodarone induced pulmonary toxicity has an incidence of about 5%-10%, and it is considered the most serious adverse effect with mortalities reaching up to 10% of the patients.

PULMONARY TOXICITY

See full prescribing information for complete boxed warning.

Our database has 144 adverse reactions for this drug across the following areas

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SKIN.
HAIR.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of amiodarone in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 08/02/2021

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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