Dabigatran

BreastfeedingGeriatricPediatric
  • TRADE NAME: Pradaxa (Boehringer Ingelheim)
  • INDICATIONS: Prevention of venous thromboembolic events, reduce stroke risk
  • CLASS: Anticoagulant, Thrombin inhibitor
  • HALF-LIFE: 2.5 days
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Amiodarone, Antacids, Anticoagulants, Atorvastatin, Carbamazepine, Clarithromycin, Clopidogrel, Collagenase, Cyclosporine, Darunavir, Dasatinib, Deferasirox, Desirudin, Dextran, Diclofenac, Dronedarone, Fondaparinux, Heparin, Ibritumomab, Itraconazole, Ketoconazole, Ketorolac, Lapatinib, Meloxicam, Nandrolone, Neratinib, NSAIDs, P-glycoprotein inducers and inhibitors, Pantoprazole, Pentosan, Phenytoin, Polysulfate sodium, Prostacyclin analogues, Proton pump inhibitors, Quinidine, Rifampin, Rivaroxaban, Salicylates, St John's Wort, Sulfinpyrazone, Tacrolimus, Telaprevir, Thrombolytic agents, Ticlopidine, Tipranavir, Tositumomab & Iodine131, Ulipristal, Verapamil, Vitamin K antagonists

PREGNANCY CATEGORY: C

Contra-indicated in patients with active pathological bleeding or with a mechanical prosthetic heart valve.

DISCONTINUING PRADAXA IN PATIENTS WITHOUT ADEQUATE CONTINUOUS ANTICOAGULATION INCREASES RISK OF STROKE

See full prescribing information for complete boxed warning.

Our database has 47 adverse reactions for this drug across the following areas

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SKIN
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
ENDOCRINE/METABOLIC
GASTROINTESTINAL/HEPATIC
GENITOURINARY
HEMATOLOGIC
OCULAR
RENAL
RESPIRATORY
OTHER


Page last updated 11/30/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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