Tipranavir

BreastfeedingGeriatricPediatric
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Abacavir, Alcohol, Alfuzosin, Alprazolam, Amiodarone, Antacids, Antifungals, Apixaban, Artemether/Lumefantrine, Atazanavir, Atomoxetine, Atorvastatin, Bepridil, Bosentan, Buprenorphine, Calcium channel blockers, Carbamazepine, Cisapride, Clarithromycin, Codeine, Conivaptan, Copanlisib, Corticosteroids, Cyclosporine, CYP2D6 substrates, CYP3A4 inducers, Dabigatran, Darifenacin, Deferasirox, Delavirdine, Didanosine, Digoxin, Dihydroergotamine, Disulfiram, Efavirenz, Elbasvir & Grazoprevir, Eluxadoline, Enfuvirtide, Eplerenone, Ergotamine, Esomeprazole, Estradiol, Estrogens, Etravirine, Fesoterodine, Flecainide, Fluconazole, Fosamprenavir, Fusidic Acid, Garlic, HMG-CoA reductase inhibitors, Lopinavir, Lovastatin, Meperidine, Methadone, Metoprolol, Metronidazole, Midazolam, Midostaurin, Nebivolol, Nefazodone, Neratinib, Omeprazole, P-glycoprotein substrates, Pantoprazole, Phenobarbital, Phenytoin, Pimozide, Propafenone, Protease inhibitors, Proton pump inhibitors, Quetiapine, Quinidine, Quinine, Raltegravir, Ranolazine, Rifabutin, Rifampin, Rilpivirine, Rivaroxaban, Rosuvastatin, Salmeterol, Saquinavir, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sofosbuvir, Sofosbuvir/Velpatasvir/Voxilaprevir, St John's Wort, Tacrolimus, Tamoxifen, Telithromycin, Temsirolimus, Tenofovir Disoproxil, Tetrabenazine, Theophylline, Thioridazine, Tramadol, Trazodone, Triazolam, Tricyclic antidepressants, Valproic Acid, Vardenafil, Viloxazine, Vitamin E, Zidovudine

PREGNANCY CATEGORY: C

NOTE

Tipranavir is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.

Tipranavir is co-administered with ritonavir.

Contra-indicated in patients with moderate or severe (Child-Pugh Class B or C) hepatic impairment.

BLACK BOX WARNING
HEPATOTOXICITY and INTRACRANIAL HEMORRHAGE

See full prescribing information for complete boxed warning.

Our database has 56 adverse reactions for this drug across the following areas

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SKIN.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.


Page last updated 07/31/2023

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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