Investigated for treating COVID-19.
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- TRADE NAMES: Revatio (Pfizer); Viagra (Pfizer)
- INDICATIONS: Erectile dysfunction, hypertension
- CLASS: Covid-19 putative drug, Phosphodiesterase type 5 (PDE5) inhibitor
- HALF-LIFE: 4 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alfuzosin, Alpha blockers, Amlodipine, Amprenavir, Amyl Nitrite, Antifungals, Antihypertensives, Atazanavir, Boceprevir, Bosentan, Cimetidine, Clarithromycin, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Conivaptan, CYP3A4 inhibitors and inducers, Darunavir, Dasatinib, Deferasirox, Delavirdine, Disopyramide, Erythromycin, Etravirine, Fosamprenavir, Grapefruit Juice, High-fat foods, HMG-CoA reductase inhibitors, Indinavir, Isosorbide, Isosorbide Dinitrate, Isosorbide Mononitrate, Itraconazole, Ketoconazole, Lopinavir, Macrolide antibiotics, Nelfinavir, Nicorandil, Nitrates, Nitroglycerin, Ombitasvir/Paritaprevir/Ritonavir, Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir, Other phosphodiesterase 5 inhibitors, Paclitaxel, PEG-Interferon, Riociguat, Ritonavir, Sapropterin, Saquinavir, St John's Wort, Telaprevir, Telithromycin, Tipranavir, Vericiguat
- See adverse reactions attributed to class:
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Page last updated 01/30/2025
