Ritonavir

Breastfeeding
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Abiraterone, Afatinib, Alfentanil, Alfuzosin, Alprazolam, Amiodarone, Amitriptyline, Amprenavir, Aprepitant, Astemizole, Atazanavir, Atorvastatin, Atovaquone, Atovaquone/Proguanil, Avanafil, Azithromycin, Bepridil, Boceprevir, Bosentan, Brigatinib, Buprenorphine, Bupropion, Buspirone, Cabazitaxel, Cabozantinib, Calcifediol, Carbamazepine, Ceritinib, Chlordiazepoxide, Ciclesonide, Citalopram, Clozapine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colchicine, Conivaptan, Copanlisib, Crizotinib, Cyclosporine, Cyproterone, Darifenacin, Dasatinib, Deferasirox, Delavirdine, Diazepam, Diclofenac, Dihydroergotamine, Docetaxel, Dronedarone, Dutasteride, Efavirenz, Eletriptan, Eluxadoline, Ergot alkaloids, Ergotamine, Erlotinib, Estazolam, Estradiol, Eszopiclone, Etravirine, Everolimus, Ezetimibe, Fentanyl, Fesoterodine, Flecainide, Flibanserin, Flurazepam, Fluticasone Propionate, Glecaprevir & Pibrentasvir, Halazepam, Indacaterol, Isavuconazonium Sulfate, Itraconazole, Ivabradine, Ixabepilone, Ketoconazole, Lapatinib, Ledipasvir & Sofosbuvir, Levomepromazine, Levothyroxine, Lomitapide, Macitentan, Maraviroc, Meloxicam, Meperidine, Meptazinol, Methylergonovine, Methysergide, Midazolam, Midostaurin, Mifepristone, Naldemedine, Nelfinavir, Neratinib, Nifedipine, Nilotinib, Olaparib, Oral Contraceptives, Osimertinib, Paclitaxel, Palbociclib, Paroxetine Hydrochloride, Pazopanib, Phenytoin, Pimozide, Piroxicam, Pitavastatin, Ponatinib, Posaconazole, Propafenone, Propoxyphene, Propranolol, Quazepam, Quinidine, Quinine, Ranolazine, Ribociclib, Rifabutin, Rifampin, Rifapentine, Rilpivirine, Rimonabant, Risperidone, Rivaroxaban, Romidepsin, Rosuvastatin, Ruxolitinib, Saquinavir, Sildenafil, Silodosin, Simeprevir, Simvastatin, Sofosbuvir, Sofosbuvir/Velpatasvir/Voxilaprevir, Solifenacin, St John's Wort, Sunitinib, Tadalafil, Telaprevir, Telithromycin, Temsirolimus, Tenofovir Disoproxil, Ticagrelor, Tolvaptan, Trabectedin, Triazolam, Ulipristal, Vardenafil, Vemurafenib, Venetoclax, Vorapaxar, Voriconazole, Zolpidem, Zuclopenthixol

PREGNANCY CATEGORY: B

Protease inhibitors cause dyslipidemia which includes elevated triglycerides and cholesterol and redistribution of body fat centrally to produce the so-called 'protease paunch', breast enlargement, facial atrophy, and 'buffalo hump'.

Kaletra is ritonavir and lopinavir.

See also separate entry for ombitasvir/paritaprevir/ritonavir.

DRUG-DRUG INTERACTIONS LEADING TO POTENTIALLY SERIOUS AND/OR LIFE THREATENING REACTIONS

See full prescribing information for complete boxed warning.

Our database has 139 adverse reactions for this drug across the following areas

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SKIN
HAIR
NAILS
MUCOSAL
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
ENDOCRINE/METABOLIC
GASTROINTESTINAL/HEPATIC
GENITOURINARY
HEMATOLOGIC
NEUROMUSCULAR/SKELETAL
OCULAR
OTIC
RENAL
RESPIRATORY
OTHER


Page last updated 10/30/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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