NSAIDs may cause an increased risk of serious cardiovascular and gastrointestinal adverse events, which can be fatal. This risk may increase with duration of use.
Elderly patients are at greater risk for serious gastrointestinal events
- TRADE NAMES: Antiflog; Apo-Piroxicam; Baxo; Doblexan; Felden; Feldene (Pfizer); Larapam; Nu-Pirox; Rogal; Sotilen; Zunden
- INDICATIONS: Arthritis
- CLASS: Non-steroidal anti-inflammatory (NSAID)
- HALF-LIFE: 50 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
ACE inhibitors, Aspirin, Furosemide, Lithium, Methotrexate, Ritonavir, Warfarin - PREGNANCY: pregnancy category C prior to 30 weeks gestation; category D starting at 30 weeks gestation
- See adverse reactions attributed to class:
CARDIOVASCULAR AND GASTROINTESTINAL RISKS
See full prescribing information for complete boxed warning.
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Page last updated 07/31/2023
