Methotrexate

BreastfeedingGeriatricPediatric

August 2023: UK Medicines and Healthcare products Regulatory Agency
Methotrexate: advise patients to take precautions in the sun to avoid photosensitivity reactions
Photosensitivity reactions are known side effects of methotrexate treatment and can be
severe. Patients should be advised to take precautions to protect their skin in the sun.

SEVERE TOXIC REACTIONS, INCLUDING EMBRYOFETAL TOXICITY AND DEATH

See full prescribing information for complete boxed warning.

Our database has 233 adverse reactions for this drug across the following areas

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SKIN.
HAIR.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of methotrexate in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 02/21/2024

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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