Bismuth

  • TRADE NAMES: Bismatrol; Bismuth Iodoform Paraffin Paste (BIPP); Bismuth subcitrate; Bismuth subgallate; Bismuth sucralfate; Caved-S; Colo-Fresh; De-Nol; Devrom; Diotame; Helidac (Prometheus); Pepto-Bismol (Procter & Gamble); Pink Bismuth
  • INDICATIONS: As part of ‘triple therapy’ (antibiotics + bismuth) for eradication of H. pylori. Bismuth subgallate initiates clotting via activation of factor XII, and is used for bleeding during tonsillectomy and adenoidectomy. BIPP impregnated ribbon gauze is used for packing following ear surgery. Bismuth subsalicylate is in OTC products for gastrointestinal complaints and peptic ulcer disease.
  • CLASS: Disinfectant, Heavy metal
  • HALF-LIFE: 21–72 days
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Aspirin, Ciprofloxacin, Demeclocycline, Doxycycline, Hypoglycemics, Lomefloxacin, Lymecycline, Methotrexate, Minocycline, Tetracycline, Warfarin

PREGNANCY CATEGORY: D
category C in first and second trimesters; category D in third trimester

Our database has 48 adverse reactions for this drug across the following areas

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SKIN.
HAIR.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OTIC.
RENAL.
OTHER.


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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