Demeclocycline
- TRADE NAMES: Declomycin (ESP Pharma); Ledermicina; Ledermycin; Rynabron
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antibiotic; tetracycline, Antimicrobial
- HALF-LIFE: 10–16 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acitretin, Amoxicillin, Ampicillin, Antacids, Bacampicillin, BCG Vaccine, Bismuth, Calcium salts, Carbenicillin, Cloxacillin, Coumarins, Dairy products, Desmopressin, Digoxin, Dong Quai, Ergotamine, Kaolin, Methotrexate, Methoxyflurane, Methysergide, Mezlocillin, Nafcillin, Oral iron, Oral typhoid vaccine, Oxacillin, Penicillins, Phenindione, Piperacillin, Quinapril, Retinoids, St John's Wort, Strontium Ranelate, Sucralfate, Sulfonylureas, Ticarcillin, Tripotassium dicitratobismuthate, Zinc
PREGNANCY CATEGORY: D
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SKIN.
NAILS.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
RENAL.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
