Zinc

  • TRADE NAMES: Calamine; Cold-Eeze (The Quigley Corp); Galzin; Zicam
  • INDICATIONS: Supplement to intravenous solutions given for total parenteral nutrition (TPN)
  • CLASS: Food supplement, Trace element
  • HALF-LIFE: N/A

Zinc is found in meats, seafood, dairy products, legumes, nuts, whole grains. Zinc oxide and zinc sulfate are used to fortify wheat products.

Dermatitis 

(2003): Shimizu T+, Clin Exp Dermatol 28(6), 675 (dental fillings)

(1997): Nielsen NH+, Am J Contact Dermat 8(3), 170 (zinc pyrithione shampoo)

(1988): Nigam PK+, Contact Dermatitis 19(3), 219 (zinc pyrithione)

(1979): Muston HL+, Contact Dermatitis 5(4), 276 (zinc pyrithione)

Erythroderma 

(1966): Babini G, Arch Ital Dermatol Venereol Sessuol 34(3), 230 (zinc dithiocarbamate)

Palmoplantar pustulosis 

(2005): Yanagi T+, Lancet 366(9490), 1050 (dental fillings)

Pigmentation 

(2002): Greenberg JE+, J Cutan Pathol 29(10), 613

Oral lichen planus 

(2002): Ido T+, Contact Dermatitis 47(1), 51

Oral mucosal irritation 

(1998): Garland ML+, Ann Pharmacother 32(1), 63 [REVIEW] (zinc gluconate)

(1984): Eby GA+, Antimicrob Agents Chemother 25(1), 20 (zinc gluconate)

Anosmia (smell loss) / smell disorder 

(2006): Davidson TM, Laryngoscope 116(9), 1721 (intranasal)

(2006): Seidman MD, Laryngoscope 116(9), 1720 (intranasal)

Dysgeusia (taste perversion) 

(1998): Garland ML+, Ann Pharmacother 32(1), 63 [REVIEW] (zinc gluconate)

(1996): Mossad SB+, Ann Intern Med 125(2), 81 (zinc gluconate)

(1984): Eby GA+, Antimicrob Agents Chemother 25(1), 20-4 (zinc gluconate)

(1982): Rasker JJ+, Scand J Rheumatol 11(3), 168 (zinc sulfate)

(1980): Zetin M+, Clin Nephrol 13(1), 20-5

Headache 

(1987): Samman S+, Med J Aust 146(5), 246

Abdominal pain 

(1987): Samman S+, Med J Aust 146(5), 246

Gastric mucosal injury 

(2022): Iwamuro M+, Nihon Shokakibyo Gakkai Zasshi (Japanese) 119(9), 853-857 (1 case / male)Geriatric

Infusion-site irritation 

(2021): Patel O+, J Med Virol Feb, Online ahead of print (3 cases ) (Zinc chloride solution administered iv)

Asthenia / fatigue 

(2002): Igic PG+, Mayo Clin Proc 77(7), 713

Cancer 

(2007): Gallus S+, Eur Urol 52(4), 1052 (prostate)



Page last updated 10/18/2022

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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