Levofloxacin

BreastfeedingGeriatric
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alfuzosin, Aminophylline, Amiodarone, Antacids, Antidiabetics, Arsenic, Artemether/Lumefantrine, BCG Vaccine, Chloroquine, Ciprofloxacin, Corticosteroids, Cyclosporine, Didanosine, Dronedarone, Gadobutrol, Insulin, Lanthanum, Mycophenolate, Nilotinib, NSAIDs, Oral iron, Oral typhoid vaccine, Phenindione, Pimozide, Probenecid, QT prolonging agents, Quinine, Strontium Ranelate, Sucralfate, Sulfonylureas, Tetrabenazine, Thioridazine, Vitamin K antagonists, Warfarin, Zinc, Ziprasidone, Zolmitriptan

PREGNANCY CATEGORY: C

Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.

Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.

Levofloxacin is the levo- or (S)-isomer of the racemic form, Ofloxacin. See Ofloxacin for the adverse reactions of the racemic form.

SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRIAL NERVOUS SYSTEM EFFECTS and EXACERBATION OF MYASTHENIA GRAVIS

See full prescribing information for complete boxed warning.

Our database has 108 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.


Page last updated 08/18/2021

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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