Levofloxacin
- TRADE NAMES: Iquix (Santen); Levaquin (Ortho-McNeil); Quixin (Johnson & Johnson); Tavanic (Sanofi-Aventis)
- INDICATIONS: Various infections caused by susceptible organisms, inhalational anthrax (post exposure)
- CLASS: Antibiotic, Antibiotic; fluoroquinolone, Antibiotic; quinolone, Antimicrobial, Drug-resistant antituberculosis agent
- HALF-LIFE: 6–8 hours
Alfuzosin, Aminophylline, Amiodarone, Antacids, Antidiabetics, Arsenic, Artemether/Lumefantrine, BCG Vaccine, Chloroquine, Ciprofloxacin, Corticosteroids, Cyclosporine, Didanosine, Dronedarone, Gadobutrol, Insulin, Lanthanum, Mycophenolate, Nilotinib, NSAIDs, Oral iron, Oral typhoid vaccine, Phenindione, Pimozide, Probenecid, QT prolonging agents, Quinine, Strontium Ranelate, Sucralfate, Sulfonylureas, Tetrabenazine, Thioridazine, Vitamin K antagonists, Warfarin, Zinc, Ziprasidone, Zolmitriptan
PREGNANCY CATEGORY: C
Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.
Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.
Levofloxacin is the levo- or (S)-isomer of the racemic form, Ofloxacin. See Ofloxacin for the adverse reactions of the racemic form.
See full prescribing information for complete boxed warning.
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Page last updated 09/01/2023
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Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
