Artemether/Lumefantrine
- TRADE NAME: Coartem (Novartis)
- INDICATIONS: Acute, uncomplicated malaria infections due to Plasmodium falciparum in patients of 5kg bodyweight and above
- CLASS: Antimalarial
- HALF-LIFE: ~2 hours (artemether); 3–6 days (lumefantrine)
Amiodarone, Amitriptyline, Amoxapine, Antimalarials, Antiretrovirals, Arsenic, Astemizole, Atazanavir, Atovaquone/Proguanil, Azithromycin, Carbamazepine, Ciprofloxacin, Citalopram, Clomipramine, Conivaptan, CYP2D6 substrates, CYP3A4 inducers, inhibitors or substrates, Darunavir, Dasatinib, Degarelix, Delavirdine, Disopyramide, Dolasetron, Duloxetine, Flecainide, Halofantrine, Hormonal contraceptives, Imipramine, Indinavir, Itraconazole, Lapatinib, Levofloxacin, Levomepromazine, Lopinavir, Mefloquine, Moxifloxacin, Nelfinavir, Norfloxacin, Ofloxacin, Paroxetine Hydrochloride, Pazopanib, Phenytoin, Pimozide, Procainamide, Quinidine, Quinine, Rifampin, Risperidone, Sotalol, St John's Wort, Telavancin, Telithromycin, Terfenadine, Tipranavir, Venlafaxine, Voriconazole, Vorinostat, Ziprasidone, Zuclopenthixol
PREGNANCY CATEGORY: C
Artemether/Lumefantrine tablets should not be used to treat severe malaria or to prevent malaria.
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Page last updated 10/11/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
