- TRADE NAME: Vfend (Pfizer)
- INDICATIONS: Invasive aspergillosis
- CLASS: Antifungal / antimycotic, Antifungal; triazole, Antimicrobial, CYP3A4 inhibitor
- HALF-LIFE: 6–24 hours (dose dependent)
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Abiraterone, Alfentanil, Alfuzosin, Almotriptan, Alosetron, Amphotericin B, Antineoplastics, Apixaban, Aprepitant, Artemether/Lumefantrine, Astemizole, Atazanavir, Atorvastatin, Barbiturates, Benzodiazepines, Boceprevir, Bortezomib, Bosentan, Brigatinib, Brinzolamide, Buspirone, Busulfan, Cabazitaxel, Cabozantinib, Calcifediol, Calcium channel blockers, Carbamazepine, Carvedilol, Chloramphenicol, Chloroquine, Ciclesonide, Cilostazol, Cinacalcet, Ciprofloxacin, Cisapride, Clopidogrel, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Colchicine, Conivaptan, Copanlisib, Coumarins, Crizotinib, Cyclosporine, CYP2C19 inhibitors and inducers, CYP2C9 inhibitors and substrates, CYP3A4 substrates, Darunavir, Diazepam, Diclofenac, Didanosine, Dienogest, Docetaxel, Dofetilide, Dronedarone, Dutasteride, Efavirenz, Eletriptan, Eplerenone, Ergot alkaloids, Ergotamine, Erlotinib, Esomeprazole, Estrogens, Eszopiclone, Etravirine, Everolimus, Fentanyl, Fesoterodine, Food, Gadobutrol, Gefitinib, Grapefruit Juice, Guanfacine, Halofantrine, HMG-CoA reductase inhibitors, Ibrutinib, Ibuprofen, Imatinib, Irinotecan, Ixabepilone, Lapatinib, Letermovir, Lomitapide, Lopinavir, Losartan, Lumateperone, Macrolide antibiotics, Maraviroc, Meloxicam, Methadone, Methylergonovine, Methylprednisolone, Methysergide, Midazolam, Midostaurin, Mifepristone, Mometasone, Neratinib, Nilotinib, Nisoldipine, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Omeprazole, Oxycodone, Palbociclib, Pantoprazole, Paricalcitol, Pazopanib, PEG-Interferon, Phenobarbital, Phenytoin, Phosphodiesterase 5 inhibitors, Pimecrolimus, Pimozide, Ponatinib, Prasugrel, Progestins, Progestogens, Protease inhibitors, Proton pump inhibitors, QT prolonging agents, Quetiapine, Quinidine, Quinine, Ramelteon, Ranolazine, Reboxetine, Regorafenib, Repaglinide, Ribociclib, Rifabutin, Rifampin, Rifapentine, Rilpivirine, Ritonavir, Rivaroxaban, Romidepsin, Ruxolitinib, Salmeterol, Saquinavir, Saxagliptin, Silodosin, Simeprevir, Simvastatin, Sirolimus, Solifenacin, Sonidegib, Sorafenib, St John's Wort, Sucralfate, Sulfonylureas, Sunitinib, Tacrolimus, Tadalafil, Tamsulosin, Telaprevir, Temsirolimus, Tetrabenazine, Tezacaftor/Ivacaftor, Thioridazine, Ticagrelor, Tolterodine, Tolvaptan, Vemurafenib, Venetoclax, Venlafaxine, Vitamin K antagonists, Ziprasidone, Zolpidem
- See adverse reactions attributed to class:
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Page last updated 08/13/2024
