Oxycodone

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Endocodone; OxyContin (Purdue); OxyIR (Purdue); Percocet (Endo); Roxicodone (aaiPharma); Supeudol; Targiniq (Purdue); Troxyca (Pfizer); Tylox (Ortho-McNeil); Xtampza ER (Collegium)
  • INDICATIONS: Pain
  • CLASS: Opiate agonist
  • HALF-LIFE: 4.6 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Cimetidine, Clonazepam, Telithromycin, Voriconazole

PREGNANCY CATEGORY: B

Oxycodone is often combined with acetaminophen (Percocet, Roxicet, Tylox) or aspirin (Percodan, Roxiprin); Targiniq is oxycodone and naloxone; Troxyca is oxycodone and naltrexone.

Contra-indicated in patients with significant respiratory depression, acute or severe bronchial asthma, or with known or suspected gastrointestinal obstruction, including paralytic ileus.

ADDICTION, ABUSE and MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and CYTOCHROME P450 3A4 INTERACTION

See full prescribing information for complete boxed warning.

Our database has 56 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
LOCAL.
NEUROMUSCULAR/SKELETAL.
RESPIRATORY.
OTHER.


Page last updated 08/02/2021

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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