Oxycodone is often combined with acetaminophen (Percocet, Roxicet, Tylox) or aspirin (Percodan, Roxiprin); Targiniq is oxycodone and naloxone; Troxyca is oxycodone and naltrexone.
Contra-indicated in patients with significant respiratory depression, acute or severe bronchial asthma, or with known or suspected gastrointestinal obstruction, including paralytic ileus.
- TRADE NAMES: Endocodone; OxyContin (Purdue); OxyIR (Purdue); Percocet (Endo); Roxicodone (aaiPharma); Supeudol; Targiniq (Purdue); Troxyca (Pfizer); Tylox (Ortho-McNeil); Xtampza ER (Collegium)
- INDICATIONS: Pain
- CLASS: Opiate agonist
- HALF-LIFE: 4.6 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Cimetidine, Clonazepam, Telithromycin, Voriconazole
- See adverse reactions attributed to class:
ADDICTION, ABUSE and MISUSE; LIFE-THREATENING RESPIRATORY DEPRESSION; ACCIDENTAL INGESTION; NEONATAL OPIOID WITHDRAWAL SYNDROME; and CYTOCHROME P450 3A4 INTERACTION
See full prescribing information for complete boxed warning.
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Page last updated 08/09/2024
