Methylprednisolone
- TRADE NAMES: Advantan (Intendis); Medrol (Pharmacia); Solu-Medrol (Pharmacia)
- INDICATIONS: Arthralgias, asthma, dermatoses, inflammatory ocular conditions, rhinitis
- CLASS: Corticosteroid / Glucocorticoid, Corticosteroid, systemic, Covid-19 putative drug
- HALF-LIFE: 12–36 hours; 2–4 hours (plasma)
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Aminophylline, Aprepitant, Aspirin, Carbamazepine, Clarithromycin, Conivaptan, Cyclosporine, Daclizumab, Darunavir, Delavirdine, Erythromycin, Indinavir, Itraconazole, Ketoconazole, Live vaccines, Oral Contraceptives, Phenobarbital, Phenytoin, Rifampin, Telaprevir, Telithromycin, Troleandomycin, Voriconazole, Warfarin
PREGNANCY CATEGORY: C
Investigated for treating COVID-19.
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 12/24/2023
Symbol key
Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric