Venlafaxine
- TRADE NAMES: Effexor (Wyeth); Effexor XL (Wyeth)
- INDICATIONS: Major depressive disorder
- CLASS: Antidepressant, Serotonin-norepinephrine reuptake inhibitor
- HALF-LIFE: 3–7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
5HT1 agonists, Artemether/Lumefantrine, Aspirin, Atomoxetine, Clozapine, Desvenlafaxine, Dexibuprofen, Diclofenac, Duloxetine, Entacapone, Haloperidol, Indinavir, Isocarboxazid, Ketoconazole, Linezolid, Lithium, MAO inhibitors, Meloxicam, Metoclopramide, Metoprolol, Mirtazapine, Moclobemide, Naratriptan, NSAIDs, Phenelzine, Selegiline, Sibutramine, SNRIs, SSRIs, St John's Wort, Sumatriptan, Tramadol, Tranylcypromine, Trazodone, Trimipramine, Triptans, Viloxazine, Voriconazole, Warfarin
PREGNANCY CATEGORY: C
SUICIDALITY AND ANTIDEPRESSANT DRUGS
See full prescribing information for complete boxed warning.
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SKIN.
HAIR.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 08/10/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
