Sumatriptan

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Alsuma (King); Imigran (GSK); Imitrex (GSK); Onzetra Xsail (Avanir); Sumavel DosePro (Endo); Zecuity (Teva)
  • INDICATIONS: Migraine attacks, cluster headaches
  • CLASS: 5-HT1 agonist, Serotonin receptor agonist, Triptan
  • HALF-LIFE: 2.5 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Citalopram, Dihydroergotamine, Ergot-containing drugs, Escitalopram, Fluoxetine, Fluvoxamine, Isocarboxazid, MAO inhibitors, Methysergide, Naratriptan, Nefazodone, Paroxetine Hydrochloride, Phenelzine, Rizatriptan, Sertraline, Sibutramine, SNRIs, SSRIs, St John's Wort, Tranylcypromine, Venlafaxine, Zolmitriptan

PREGNANCY CATEGORY: C

Contra-indicated in patients with Wolff-Parkinson-White syndrome, peripheral vascular disease, ischemic bowel disease, uncontrolled hypertension, severe hepatic impairment or a history of coronary artery disease, coronary vasospasm, stroke, transient ischemic attack, or hemiplegic or basilar migraine; or with recent (within 24 hours) use of another 5-HT1 agonist (e.g. another triptan) or an ergotamine-containing medication, or current or recent (past 2 weeks) use of a monoamine oxidase-A inhibitor.

Our database has 105 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.


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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of sumatriptan in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)

Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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