Sertraline
- TRADE NAMES: Atruline; Zoloft (Pfizer)
- INDICATIONS: Depression, panic disorders, obsessive compulsive disorders
- CLASS: Antidepressant, Selective serotonin reuptake inhibitor (SSRI)
- HALF-LIFE: 24–26 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amphetamines, Astemizole, Clarithromycin, Clozapine, Darunavir, Dextroamphetamine, Diethylpropion, Droperidol, Efavirenz, Erythromycin, Gilteritinib, Isocarboxazid, Linezolid, MAO inhibitors, Mazindol, Methamphetamine, Metoclopramide, Phendimetrazine, Phenelzine, Phentermine, Phenylpropanolamine, Pimozide, Pseudoephedrine, Selegiline, Sibutramine, St John's Wort, Sumatriptan, Sympathomimetics, Tranylcypromine, Trazodone, Troleandomycin, Zolmitriptan
PREGNANCY CATEGORY: C
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SKIN.
HAIR.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTIC.
RENAL.
RESPIRATORY.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
