Linezolid
- TRADE NAME: Zyvox (Pfizer)
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antibiotic; oxazolidinone, Antimicrobial
- HALF-LIFE: 4–5 hours
Alcohol, Alpha blockers, Altretamine, Amitriptyline, Amoxapine, Amphetamines, Anilidopiperidine opioids, Antihypertensives, Atomoxetine, Beta blockers, Buprenorphine, Bupropion, Buspirone, Caffeine, Carbamazepine, Clomipramine, Cyclobenzaprine, Desipramine, Desvenlafaxine, Dexmethylphenidate, Dextromethorphan, Diethylpropion, Doxapram, Doxepin, Fluoxetine, Fluvoxamine, Hydromorphone, Imipramine, Levodopa, Lithium, MAO inhibitors, Maprotiline, Meperidine, Methadone, Methyldopa, Methylphenidate, Mirtazapine, Nortriptyline, Oral typhoid vaccine, Ozanimod, Paroxetine Hydrochloride, Paroxetine Mesylate, Paroxetine Mesylate, Propoxyphene, Protriptyline, Reserpine, Rifampin, Safinamide, Serotonin 5-HT1D receptor agonists, Serotonin/norepinephrine reuptake inhibitors, Sertraline, Sibutramine, SSRIs, Tapentadol, Tetrabenazine, Tetrahydrozoline, Tramadol, Trazodone, Tricyclic antidepressants, Trimipramine, Tryptophan, Venlafaxine
PREGNANCY CATEGORY: C
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of linezolid in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 03/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
