Suboxone is buprenorphine and naloxone.
Probuphine is an implant for subdermal administration.
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- TRADE NAMES: Probuphine (Braeburn); Suboxone (Reckitt Benckiser); Subutex (Reckitt Benckiser); Temgesic; Transtec (Napp)
- INDICATIONS: Opioid dependence, moderate to severe pain
- CLASS: Analgesic, Mixed opioid agonist/antagonist, Narcotic
- HALF-LIFE: 37 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Antihistamines, Atazanavir, Azole antifungals, Benzodiazepines, Boceprevir, Carbamazepine, Cimetidine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Delavirdine, Diazepam, Efavirenz, Erythromycin, HIV protease inhibitors, Hydrocodone, Hydromorphone, Ketoconazole, Ketorolac, Linezolid, Macrolide antibiotics, Morphine, Neuroleptics, Oliceridine, Oxymorphone, Phenobarbital, Phenytoin, Rifampin, Ritonavir, Tapentadol, Tipranavir
- See adverse reactions attributed to class:
ABUSE POTENTIAL, LIFE-THREATENING RESPIRATORY DEPRESSION, and ACCIDENTAL EXPOSURE
Probuphine: IMPLANT MIGRATION, PROTRUSION, EXPULSION, and NERVE DAMAGE ASSOCIATED WITH INSERTION and REMOVAL
See full prescribing information for complete boxed warning.
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Page last updated 11/26/2024
