Desipramine
- TRADE NAMES: Deprexan; Nebril; Norpramin (Sanofi-Aventis); Nortimil; Pertofran; Pertofrane; Petylyl; PMS-Desipramine
- INDICATIONS: Depression
- CLASS: Antidepressant; tricyclic, Norepinephrine reuptake inhibitor
- HALF-LIFE: 7–60 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amprenavir, Arbutamine, Boceprevir, Buspirone, Cinacalcet, Clonidine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Epinephrine, Fentanyl, Fluoxetine, Formoterol, Guanethidine, Isocarboxazid, Linezolid, Lithium, MAO inhibitors, Mirabegron, Phenelzine, Quinolones, Sparfloxacin, St John's Wort, Telaprevir, Terbinafine, Tramadol, Tranylcypromine, Tricyclic antidepressants, Tryptophan, Viloxazine
PREGNANCY CATEGORY: C
SUICIDALITY AND ANTIDEPRESSANT DRUGS
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SKIN.
HAIR.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
NEUROMUSCULAR/SKELETAL.
OTHER.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
