June 2024. Tramadol and warfarin drug interaction. The UK MHRA issued the following advice:
Taking warfarin and tramadol together can cause harmful drug interactions, which can raise the International Normalised Ratio (INR), and result in severe bruising and bleeding, which in some patients could be fatal.
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- TRADE NAMES: Contramal; Rybix ODT (Victory Pharma); Tadol; Tradol; Tramal; Tramed; Tramol; Tridol; Ultracet (Ortho-McNeil); Ultram (Ortho-McNeil); Zipan
- INDICATIONS: Pain
- CLASS: Opiate agonist
- HALF-LIFE: 6–7 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alcohol, Amitriptyline, Carbamazepine, Cinacalcet, Citalopram, Delavirdine, Desflurane , Desipramine, Desvenlafaxine, Duloxetine, Erythromycin, Fluoxetine, Fluvoxamine, Ketoconazole, Levomepromazine, Linezolid, Lorcaserin, MAO inhibitors, Nefazodone, Ondansetron, Paroxetine Hydrochloride, Phenelzine, Quinidine, Risperidone, Safinamide, Selegiline, Selegiline, Tapentadol, Terbinafine, Tianeptine, Tipranavir, Tranylcypromine, Venlafaxine, Vilazodone, Warfarin, Zuclopenthixol
- See adverse reactions attributed to class:
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Page last updated 07/24/2024
