Tetrabenazine

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Nitoman (aaiPharma); Xenazine (Alliance)
  • INDICATIONS: Hyperkinetic movement disorders: Huntington's chorea, hemiballismus, senile chorea, Tourette syndrome, and tardive dyskinesia
  • CLASS: Vesicular monoamine transporter 2 inhibitor
  • HALF-LIFE: 2–8 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Amantadine, Amiodarone, Amitriptyline, Amoxapine, Antiarrhythmics, Antibiotics, Antipsychotics, Arsenic, Chlorpromazine, Cinacalcet, Citalopram, Cyclic antidepressants, Dasatinib, Degarelix, Delavirdine, Deutetrabenazine, Dolasetron, Haloperidol, Lapatinib, Levodopa, Levofloxacin, Levomepromazine, Linezolid, Lithium, Lurasidone, MAO inhibitors, Metoclopramide, Moxifloxacin, Olanzapine, Paliperidone, Paroxetine Hydrochloride, Pazopanib, Procainamide, QT prolonging drugs, Quinidine, Reserpine, Risperidone, Sotalol, Telavancin, Telithromycin, Terbinafine, Thioridazine, Tipranavir, Voriconazole, Vorinostat, Ziprasidone, Zuclopenthixol

PREGNANCY CATEGORY: N/A
Based on animal data, may cause fetal harm

DEPRESSION AND SUICIDALITY

See full prescribing information for complete boxed warning.

Our database has 49 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RESPIRATORY.


Page last updated 07/31/2023

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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