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- TRADE NAMES: Avelox (Bayer); Moxeza (Alcon)
- INDICATIONS: Various infections caused by susceptible organisms
- CLASS: Antibiotic, Antibiotic; fluoroquinolone, Antimicrobial, Drug-resistant antituberculosis agent
- HALF-LIFE: 12 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alfuzosin, Aminophylline, Amiodarone, Amitriptyline, Antacids, Arsenic, Artemether/Lumefantrine, Asenapine, Atomoxetine, BCG Vaccine, Benperidol, Bepridil, Bretylium, Chloroquine, Ciprofloxacin, Corticosteroids, Cyclosporine, Degarelix, Didanosine, Disopyramide, Dronedarone, Droperidol, Erythromycin, Gadobutrol, Haloperidol, Hydroxychloroquine, Insulin, Lanthanum, Levomepromazine, Magnesium salts, Mefloquine, Mizolastine, Mycophenolate, Nilotinib, NSAIDs, Oral iron, Oral typhoid vaccine, Pentamidine, Phenothiazines, Pimavanserin, Pimozide, Probenecid, Procainamide, QT prolonging agents, Quinapril, Quinidine, Quinine, Ribociclib, Sevelamer, Sotalol, Strontium Ranelate, Sucralfate, Sulfonylureas, Tetrabenazine, Thioridazine, Tricyclic antidepressants, Vandetanib, Vitamin K antagonists, Warfarin, Zinc, Ziprasidone, Zolmitriptan, Zuclopenthixol
- See adverse reactions attributed to class:
Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.
Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.
Moxeza is for topical ophthalmic use only.
SERIOUS ADVERSE REACTIONS INCLUDING TENDINITIS, TENDON RUPTURE, PERIPHERAL NEUROPATHY, CENTRAL NERVOUS SYSTEM EFFECTS and EXACERBATION OF MYASTHENIA GRAVIS
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Page last updated 09/14/2024
