Methyldopa
- TRADE NAMES: Aldoclor (Merck); Aldomet; Aldoril; Amodopa; Densul; Dopamet; Equibar; Hydopa; Medimet; Nu-Medopa; Polinal; Presinol; Prodopa
- INDICATIONS: Hypertension
- CLASS: Adrenergic alpha-receptor agonist
- HALF-LIFE: 1.7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acebutolol, Alfuzosin, Bromocriptine, Captopril, Cilazapril, Cyclopenthiazide, Diclofenac, Enalapril, Ephedrine, Fosinopril, Irbesartan, Levodopa, Levomepromazine, Linezolid, Lisinopril, Meloxicam, Olmesartan, Quinapril, Ramipril, Risperidone, Rotigotine, Trandolapril, Triamcinolone, Zuclopenthixol
PREGNANCY CATEGORY: B
Aldoril is methyldopa and hydrochlorothiazide.
Hydrochlorothiazide is a sulfonamide and can be absorbed systemically. Sulfonamides can produce severe, possibly fatal, reactions such as toxic epidermal necrolysis and Stevens-Johnson syndrome.
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SKIN.
MUCOSAL.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
HEMATOLOGIC.
NEUROMUSCULAR/SKELETAL.
RENAL.
Page last updated 07/31/2023
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
