Propoxyphene

  • TRADE NAMES: Algafan; Antalvic; Darvocet-N (Xanodyne); Darvon (Xanodyne); Darvon Compound (Xanodyne); Develin; Dolotard; Doloxene; Liberan; Parvon
  • INDICATIONS: Pain
  • CLASS: Opiate agonist
  • HALF-LIFE: 8–24 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Alprazolam, Amitriptyline, Carbamazepine, Insulin Aspart, Insulin Degludec, Insulin Glargine, Insulin Glulisine, Linezolid, Lisdexamfetamine, Metoprolol, Phenelzine, Ritonavir, Safinamide, Selegiline, Warfarin

PREGNANCY CATEGORY: C
category D with prolonged use

Darvocet is propoxyphene and acetaminophen; Darvon Compound is propoxyphene and aspirin.

This drug has been withdrawn from the European market. Xanodyne has voluntarily removed its products from the US market. The FDA is advising healthcare professionals to stop prescribing propoxyphene to their patients.

Our database has 21 adverse reactions for this drug across the following areas

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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
LOCAL.
NEUROMUSCULAR/SKELETAL.
OCULAR.
OTHER.


Page last updated 08/01/2022

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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