Entacapone


- TRADE NAMES: Comtan (Orion); Comtess (Orion); Stalevo (Orion)
- INDICATIONS: Parkinsonism
- CLASS: Catechol-O-methyl transferase inhibitor
- HALF-LIFE: 2.4 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Amitriptyline, MAO inhibitors, Paroxetine Hydrochloride, Phenelzine, Rasagiline, Tranylcypromine, Venlafaxine
PREGNANCY CATEGORY: C
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SKIN.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RESPIRATORY.
OTHER.
Page last updated 08/02/2021
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations 
- Breast feeding
- Geriatric
- Pediatric