Methylergonovine
- TRADE NAME: Methergine (Novartis)
- INDICATIONS: Routine management after delivery of placenta, postpartum atony and hemorrhage; subinvolution
- CLASS: Ergot alkaloid
- HALF-LIFE: 1.5–12.7 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alkaloid drugs, Amprenavir, Boceprevir, Clarithromycin, CYP3A4 inhibitors, Delavirdine, Dihydroergotamine, Ergotamine, Erythromycin, Indinavir, Itraconazole, Ketoconazole, Lopinavir, Nefazodone, Nelfinavir, Ombitasvir/Paritaprevir/Ritonavir, Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir, Ritonavir, Telaprevir, Troleandomycin, Voriconazole, Zileuton
PREGNANCY CATEGORY: C
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CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
GASTROINTESTINAL/HEPATIC.
RESPIRATORY.
Page last updated 08/01/2022
Symbol key
Incidence 
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Seriousness
- Hospitalization possible
- Life threatening
- Fatal
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric
