Investigated for treating COVID-19.
Kaletra is lopinavir and ritonavir.
- TRADE NAMES: Aluvira; Kaletra (AbbVie)
- INDICATIONS: HIV-1 infected children above the age of 2 years and adults, in combination with other antiretroviral agents
- CLASS: Antiretroviral, Covid-19 putative drug, HIV-1 protease inhibitor
- HALF-LIFE: 5–6 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Abacavir, Alfuzosin, Amiodarone, Amprenavir, Aripiprazole, Artemether/Lumefantrine, Atazanavir, Atorvastatin, Atovaquone, Bepridil, Bosentan, Brigatinib, Bupropion, Cabozantinib, Carbamazepine, Chlorpheniramine, Cisapride, Clarithromycin, Colchicine, Copanlisib, Cyclosporine, Darifenacin, Darunavir, Dasatinib, Delavirdine, Dexamethasone, Didanosine, Digoxin, Disulfiram, Efavirenz, Elbasvir & Grazoprevir, Eltrombopag, Eluxadoline, Ergotamine, Estradiol, Felodipine, Fentanyl, Flecainide, Fluticasone Propionate, Fosamprenavir, Glecaprevir & Pibrentasvir, Indinavir, Itraconazole, Ketoconazole, Lidocaine, Lidocaine, Lomitapide, Lovastatin, Maraviroc, Methadone, Methylergonovine, Metronidazole, Midazolam, Midostaurin, Mifepristone, Nelfinavir, Neratinib, Nevirapine, Nicardipine, Nifedipine, Nilotinib, Olaparib, Ombitasvir/Paritaprevir/Ritonavir, Palbociclib, Phenobarbital, Phenytoin, Pimozide, Pitavastatin, Ponatinib, Primidone, Quinidine, Ranolazine, Ribociclib, Rifabutin, Rifampin, Rilpivirine, Rivaroxaban, Rosuvastatin, Ruxolitinib, Salmeterol, Saquinavir, Sildenafil, Simeprevir, Simvastatin, Sirolimus, Sofosbuvir/Velpatasvir/Voxilaprevir, St John's Wort, Tacrolimus, Tadalafil, Telithromycin, Tenofovir Disoproxil, Tipranavir, Tolterodine, Trazodone, Triazolam, Vardenafil, Venetoclax, Vinblastine, Vincristine, Voriconazole, Warfarin, Zidovudine
- See adverse reactions attributed to class:
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Page last updated 03/13/2024
