Nifedipine
- TRADE NAMES: Adalat (Bayer); Adalate; Adipine; Apo-Nifed; Aprical; Calcilat; Coracten (UCB); Corogal; Corotrend; Fortipine; Hypolar; Nifecor; Nifedipress; Nu-Nifed; Pidilat; Procardia (Pfizer); Tenif (AstraZeneca); Tensipine MR (Genus); Valni XL (Winthrop)
- INDICATIONS: Angina, hypertension
- CLASS: Calcium channel blocker
- HALF-LIFE: 2–5 hours (immediate release products)
Acebutolol, Amprenavir, Atazanavir, Beta blockers, Boceprevir, Carbamazepine, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Alafenamide, Cobicistat/Elvitegravir/Emtricitabine/Tenofovir Disoproxil, Cyclosporine, Delavirdine, Digoxin, Diltiazem, Dronedarone, Efavirenz, Epirubicin, Fentanyl, Fluoxetine, Grapefruit Juice, Imatinib, Indinavir, Insulin, Lopinavir, Micafungin, Mizolastine, Nevirapine, Oxcarbazepine, Parenteral magnesium, Phenytoin, Posaconazole, Propranolol, Rifampin, Ritonavir, St John's Wort, Tacrolimus, Vardenafil, Vincristine
PREGNANCY CATEGORY: C
Although not approved for this purpose, immediate-release nifedipine capsules have been used (orally and sublingually) for acute reduction of blood pressure. The literature reports several cases of profound hypotension, myocardial infarction, and death when immediate-release nifedipine was used in this way. Immediate-release nifedipine capsules should not be used for the acute reduction of blood pressure.
Tenif is atenolol and nifedipine.
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Page last updated 07/31/2023
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Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric