Estradiol

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Alora (Watson); Climara (Bayer); Divigel (Upsher-Smith); Elestrin (Azur Pharma); Esclim (Women First); Estrace (Bristol-Myers Squibb, Warner Chilcott); Estraderm (Novartis); Estring (Pharmacia & Upjohn); Estrogel (Ascend); Evamist (KV Pharm); Fempatch (Pfizer); Gynodiol (Barr); Innofem (Novo Nordisk); Menostar (Bayer); Vagifem (Novo Nordisk); Vivelle (Novartis); Vivelle-Dot (Novartis)
  • INDICATIONS: Menopausal symptoms, hypoestrogenism due to hypogonadism, castration or primary ovarian failure, postmenopausal osteoporosis
  • CLASS: Estrogen, Hormone
  • HALF-LIFE: 1.75±2.87 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Alcohol, Amprenavir, Anastrozole, Ascorbic Acid, Atorvastatin, Boceprevir, Carbamazepine, Chenodiol, Clarithromycin, Colesevelam, Conivaptan, Corticosteroids, CYP1A2 inducers, CYP3A4 inducers, Deferasirox, Delavirdine, Erythromycin, Folic Acid, Grapefruit Juice, Itraconazole, Ketoconazole, Lopinavir, Minocycline, Oxtriphylline, P-glycoprotein inhibitors or inducers, PEG-Interferon, Phenobarbital, Rifampin, Ritonavir, Ropinirole, Saxagliptin, Somatropin, St John's Wort, Telaprevir, Thyroid products, Tipranavir, Ursodiol

PREGNANCY CATEGORY: X

See also separate entry for estrogens.

ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIA

See full prescribing information for complete boxed warning.

Our database has 16 adverse reactions for this drug across the following areas

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SKIN
CARDIOVASCULAR
CENTRAL NERVOUS SYSTEM
ENDOCRINE/METABOLIC
GASTROINTESTINAL/HEPATIC
GENITOURINARY
NEUROMUSCULAR/SKELETAL
RESPIRATORY
OTHER


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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