See also separate entry for estrogens.
- TRADE NAMES: Alora (Watson); Climara (Bayer); Divigel (Upsher-Smith); Elestrin (Azur Pharma); Esclim (Women First); Estrace (Bristol-Myers Squibb, Warner Chilcott); Estraderm (Novartis); Estring (Pharmacia & Upjohn); Estrogel (Ascend); Evamist (KV Pharm); Fempatch (Pfizer); Gynodiol (Barr); Innofem (Novo Nordisk); Menostar (Bayer); Vagifem (Novo Nordisk); Vivelle (Novartis); Vivelle-Dot (Novartis)
- INDICATIONS: Menopausal symptoms, hypoestrogenism due to hypogonadism, castration or primary ovarian failure, postmenopausal osteoporosis
- CLASS: Estrogen, Hormone
- HALF-LIFE: 1.75±2.87 hours
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Alcohol, Amprenavir, Anastrozole, Ascorbic Acid, Atorvastatin, Boceprevir, Carbamazepine, Chenodiol, Clarithromycin, Colesevelam, Conivaptan, Corticosteroids, CYP1A2 inducers, CYP3A4 inducers, Deferasirox, Delavirdine, Erythromycin, Folic Acid, Grapefruit Juice, Itraconazole, Ketoconazole, Lopinavir, Minocycline, Oxtriphylline, P-glycoprotein inhibitors or inducers, PEG-Interferon, Phenobarbital, Rifampin, Ritonavir, Ropinirole, Saxagliptin, Somatropin, St John's Wort, Telaprevir, Thyroid products, Tipranavir, Ursodiol
- See adverse reactions attributed to class:
ENDOMETRIAL CANCER, CARDIOVASCULAR DISORDERS, BREAST CANCER and PROBABLE DEMENTIA
See full prescribing information for complete boxed warning.
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Page last updated 08/20/2025
