Saxagliptin
- TRADE NAMES: Onglyza (Bristol-Myers Squibb); Qtern (AstraZeneca)
- INDICATIONS: Type II diabetes mellitus
- CLASS: Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) (gliptin) inhibitor
- HALF-LIFE: 2.5–3.1 hours
ACE inhibitors, Alcohol, Aprepitant, Beta blockers, Bexarotene, Colchicine, Conivaptan, Corticosteroids, CYP3A4 inducers, Darunavir, Dasatinib, Delavirdine, Diazoxide, Diuretics, Efavirenz, Estradiol, Estrogens, Hypoglycemic agents, Indinavir, Ketoconazole, Lapatinib, MAO inhibitors, Oxcarbazepine, P-glycoprotein inhibitors and inducers, Pegvisomant, Pioglitazone, Rifapentine, Somatropin, Strong CYP3A4/5 inhibitors, Telithromycin, Terbinafine, Testosterone, Voriconazole
PREGNANCY CATEGORY: B
Qtern is saxagliptin and dapagliflozin.
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Click on the DRUG REVIEW ARTICLE tab (above) to see a review of saxagliptin in the Taylor & Francis journal Expert Opinion on Drug Safety. (Note that non-subscribers to the journal will only be able to see an abstract of the article.)
Page last updated 07/31/2023
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Incidence
- <1%
- 1-5%
- 5-10%
- 10-15%
- 15-20%
- 20-30%
- >30%
Warnings in other populations
- Breast feeding
- Geriatric
- Pediatric