Norfloxacin

BreastfeedingGeriatricPediatric
  • TRADE NAMES: Barazan; Chibroxin (Merck); Chibroxine; Chibroxol; Lexinor; Noroxin (Merck); Oranor; Utinor; Zoroxin
  • INDICATIONS: Various urinary tract infections caused by susceptible organisms, conjunctivitis
  • CLASS: Antibiotic; fluoroquinolone, CYP3A4 inhibitor
  • HALF-LIFE: 3–4 hours
CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:

Aminophylline, Amiodarone, Antacids, Arsenic, Artemether/Lumefantrine, Bepridil, Bretylium, Caffeine, Ciprofibrate, Clozapine, Cyclosporine, Dairy products, Didanosine, Disopyramide, Erythromycin, Glyburide, Lanthanum, Mycophenolate, Nitrofurantoin, NSAIDs, Oral iron, Oral typhoid vaccine, Oxtriphylline, Phenothiazines, Probenecid, Procainamide, Quinidine, Ropinirole, Sotalol, Strontium Ranelate, Sucralfate, Tacrine, Tamoxifen, Tizanidine, Tricyclic antidepressants, Warfarin, Zinc, Zolmitriptan

PREGNANCY CATEGORY: C

Fluoroquinolones are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroid drugs, and in patients with kidney, heart or lung transplants.

Fluoroquinolones may exacerbate muscle weakness in persons with myasthenia gravis.

Our database has 38 adverse reactions for this drug across the following areas

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SKIN.
NAILS.
MUCOSAL.
CARDIOVASCULAR.
CENTRAL NERVOUS SYSTEM.
ENDOCRINE/METABOLIC.
GASTROINTESTINAL/HEPATIC.
GENITOURINARY.
NEUROMUSCULAR/SKELETAL.
OCULAR.
RENAL.
OTHER.


Page last updated 09/19/2018

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Incidence info

  • <1%
  • 1-5%
  • 5-10%
  • 10-15%
  • 15-20%
  • 20-30%
  • >30%

Seriousness info

  • Hospitalization possible
  • Life threatening
  • Fatal

Warnings in other populations info

  • Breast feeding
  • Geriatric
  • Pediatric
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