Contra-indicated in patients with significant cardiac, pulmonary, renal, hepatic, or CNS impairment.
- TRADE NAMES: Aerovent; Atem; Atronase; Narilet; Proleukin (Chiron)
- INDICATIONS: Metastatic renal cell carcinoma and metastatic melanoma
- SYNONYM: IL-2; interleukin-2
- CLASS: Biologic, Immunomodulator, Interleukin-2
- HALF-LIFE: 6–85 minutes
- CLINICALLY IMPORTANT, POTENTIALLY HAZARDOUS INTERACTIONS WITH:
Acebutolol, Alfuzosin, Altretamine, Amikacin, Aminoglycosides, Antineoplastics, Betamethasone, Bleomycin, Busulfan, Captopril, Carboplatin, Carmustine, Chlorambucil, Ciclesonide, Cilazapril, Cisplatin, Corticosteroids, Cyclophosphamide, Cytarabine, Dacarbazine, Dactinomycin, Daunorubicin, Docetaxel, Doxorubicin, Enalapril, Estramustine, Etoposide, Fludarabine, Fluorouracil, Fosinopril, Gemcitabine, Gentamicin, Hydroxyurea, Idarubicin, Ifosfamide, Indomethacin, Interferon Alfa, Irbesartan, Kanamycin, Levamisole, Lisinopril, Lomustine, Mechlorethamine, Melphalan, Mercaptopurine, Methotrexate, Mitomycin, Mitotane, Mitoxantrone, Neomycin, Olmesartan, PEG-Interferon, Pentostatin, Plicamycin, Procarbazine, Quinapril, Ramipril, Streptomycin, Streptozocin, Thioguanine, Thiotepa, Tobramycin, Trandolapril, Tretinoin, Triamcinolone, Uracil, Vinblastine, Vincristine, Vinorelbine
- See adverse reactions attributed to class:
CAPILLARY LEAK SYNDROME
See full prescribing information for complete boxed warning.
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Page last updated 07/31/2023
